Based on recent findings, electronic health record-based clinical decision support (EHR CDS) alerts didn’t increase statin prescribing in a three-arm cluster-randomized trial. While statin prescribing at guideline-recommended doses increased from 41.2% to 44.5% among cardiologists randomized to 6 months of pop-up alerts requiring action, it was no better than controls receiving no intervention (from 41.8% to 42.6%). However, the active choice intervention did lead to significantly improved statin prescribing at the optimal dose for the subgroup of patients with clinical atherosclerotic cardiovascular disease (ASCVD), reported Mitesh Patel, MD, MBA, of the University of Pennsylvania in Philadelphia, and colleagues. The active choice intervention consisted of an unchanging pop-up alert in the EHR that required cardiologists to respond by accepting or declining guideline-directed statin therapy for patients deemed not at goal according to 2013 American Heart Association/American College of Cardiology or 2015 National Lipid Association guidelines. Read more at MedPage Today.