CTSA Pilot Program

In partnership with the Institute for Translational Medicine and Therapeutics, CHIBE is inviting proposals for Clinical and Translational Science Award (CTSA) pilot projects from ITMAT Members and Associate Members in the Research Associate or Instructor A category addressing 1.) improvement of enrollment in clinical trials and 2.) improvement of health outcomes or health behavior through the use of connected health interventions.

Improving Enrollment in Clinical Trials

The concomitant problems of under‐enrollment and selective enrollment in randomized clinical trials (RCTs) often plague efforts to evaluate medical interventions. These problems often arise due to unexpected impediments to participant recruitment, which represents one of the largest costs of conducting RCTs. In recent decades, behavioral economics has provided considerable insights into how people make decisions, blending findings from economics and psychology to generate better descriptive and normative models of behavior. The goal of this pilot program is to help investigators at UPENN develop more successful strategies to increase the efficiency of clinical trial enrollment across a range of different types of interventions. Additional instructions can be found here.

Connected Health and Population Health Improvement

The proposal must center on novel approaches to testing and delivering interventions to improve health outcomes or health behavior for people at high risk for poor health outcomes. The purpose of this RFA is to support research teams to do quick turnaround studies focused on improving the management of population-based health within either clinical or non-clinical settings. While we will accept and consider all applications, applications focusing on reducing the risks from opioid addiction or atherosclerotic cardiovascular disease (ASCVD) and applications investigating the use of behavioral phenotyping are particularly encouraged and will receive special consideration.  These pilots are designed to be relatively short-term projects to create a cycle for rapid learning and iterative improvement, with a planned intervention duration for each pilot of 3-6 months.   We strongly encourage proposals to use the Way to Health platform. The PDF found here contains all documents required for submission via our Pilot Grants system.

The deadline for proposals is March 29, 2019 at noon for a project start date of June 1, 2019.

For more information on guidelines and document submission for CTSA pilot programs, visit ITMAT’s website here. For programmatic or budget questions, please contact Joelle Friedman at joellef@pennmedicine.upenn.edu